• 文献标题:   Preparation of Conjugated Polymer Dots as a Fluorescence Turn-On Assay for Bovine Serum Albumin by Interaction with Graphene Oxide
  • 文献类型:   Article
  • 作  者:   NOH J, SON S, KIM Y, CHAE BJ, KU BC, LEE TS
  • 作者关键词:   bovine serum albumin, sensor, fluorescence, conjugated polymer dot, graphene oxide
  • 出版物名称:   MOLECULAR CRYSTALS LIQUID CRYSTALS
  • ISSN:   1542-1406 EI 1563-5287
  • 通讯作者地址:   Chungnam Natl Univ
  • 被引频次:   3
  • DOI:   10.1080/15421406.2014.937287
  • 出版年:   2014

▎ 摘  要

Fluorescent conjugated polymers with various monomer compositions were synthesized via Suzuki coupling polymerization and spherically-shaped conjugated polymer dots (CPdot) with uniform size were prepared via conventional reprecipitation technique. Chemically modified graphene oxide (GO) was prepared to use as a component of sensor platform for protein detection. GO showed an excellent interaction with CPdot on its surface via hydrophobic interaction, which, in turn, induced the quenching of the fluorescence of CPdot. Upon exposure to bovine serum albumin (BSA), the quenched fluorescence was recovered, resulting from the release of CPdot from the complex with GO, as BSA adsorbed preferentially on the GO surface.