▎ 摘　　要

The TiO2-graphene (TiO2-GR) nanocomposite for paracetamol electrochemical sensing is described. The electrochemical behavior of paracetamol at the Nafion/TiO2-GR composite film modified glassy carbon electrode (GCE) was investigated by cyclic voltammetry. The results showed that the incorporation of TiO2 nanoparticles with graphene significantly enhanced the electrochemical reactivity and voltammetric response of paracetamol. In addition, Nation acts as an effective solubilizing agent and antifouling coating in the fabrication of the modified electrode. This electrochemical sensor exhibits excellent analytical performance for paracetamol detection at physiological pH with detection limit of 2.1 x 10(-7) M. linear range of 1-100 mu m and reproducibility of 3.6% relative standard deviation. (C) 2011 Elsevier B.V. All rights reserved.