▎ 摘　　要

Interfacing cells with nanomaterials such as graphene, nanowires, and carbon nanotubes is useful for the Integration of cellular physiology with electrical read outs. Here we show the interfacing of graphene sheets on the surface of yeast cells, leading to electromechanical coupling between the sheets and the cells. The cells are viable after the interfacing. The response caused by physiologically stressing the cells by exposure to alcohols, which causes a change in cell volume, can be observed in the electrical signal through graphene. The change in the cell volume leads to straining of the sheets, forming wrinkles which reduce the electrical conductivity. As the dynamic response of the cell can be observed, it Is possible to differentiate between ethanol, 2-propanol, and water. We believe this will lead to further development of cell-based electrical devices and sensors.