▎ 摘　　要

Controllable assembly of the hybrids composed of various types of nanoscale objects provides new opportunities for material fabrication. Herein, the tunable bi-functionalities of fluorescence and surface enhanced Raman scattering (SERS) signals were collected by the assembled composites of gold nanoparticles (AuNPs)/glycine derivatives (G(n), n= 0, 3, 4, 5, 6 and 9)/graphene quantum dots (GQ)Ds). The composition and structure of the AuNPs/ G(n)/GQDs composites were characterized by Fourier-transform infrared (FT-IR) spectroscopy and high resolution transmission electron microscope (HRTEM). Results indicated that the fluorescence and SERS response could be tuned effectively by changing the chain length of Gn. Also, the AuNPs/G(n)/GQDs composites could be used in a wide pH range and exhibited good stability at room and physiological temperatures. Moreover, the AuNPs/G(n)/ GQDs composites displayed low cytotoxicity in A549 cells, and the cell viability was found to be above 90% at concentrations ranging from 6.42 to 200 mu g/mL, which made AuNPs/G(n)/GQDs composites very attractive for biological imaging applications in vivo. (C) 2017 Published by Elsevier Ltd.