▎ 摘　　要

The graphene combined with New Fuchsin (NF) to prepare graphene-NF modified electrode. Graphene obtained high mechanical strength, non-antigenic biopolymer and low toxicity toward mammalian cells. Electrochemical impedance spectroscopy (EIS) applied diffusion coefficient values and some information about the kinetics of electron transfer during the redox reactions. Surface morphology of the modified electrode using scanning electron microscopy (SEM) which revealed that graphene and NF were coated on electrode. Differential pulse voltammetry (DPVs) was used for the determination of analytes. DPVs not only increased the electrocatalytic current linear concentration range, also lowered the overpotential to oxidation the interferences in the measurements. The Graphene exhibited a promising enhanced electrocatalytic activity towards analytes and enhances the loaded and stability. In this paper, the electrochemical oxidation of Cytosine (C), Thymine (T), Guanine (G) and Adenine (A) at same time.