▎ 摘　　要

In the present work, we have demonstrated the fabrication of catechol (CC) biosensor based on reduced graphene oxide (rGO) decorated beta-cyclodextrin (beta-CD) nanosheet immobilized using nafion (Nf) on modified GCE (glassy carbon electrode). The rGO/beta-CD nanocomposite is synthesized through sonochemical approach and characterized by spectral (UV-visible, FT-IR, and Raman), analytical techniques (XRD, SEM, SAED, mapping analysis, HR-TEM and EDX) and electrochemical studies. The rGO/beta-CD/Nf modified GCE exhibit a prominent electrocatalytic activity towards selective and sensitive determination of CC than other modified electrodes. Besides, the electrochemical sensor was revealed an excellent current response for the determination of CC with wide linear ranges (0.1-0.7 mu M), high sensitivity (19.1 mu A mu M(-1)cm(2)) and very low detection limit (LOD) 0.0012 mM. The excellent reproducibility, selectivity, stability, and sensitivity results are achieved for the determination of CC. (C) 2021 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.