▎ 摘　　要

Uric acid is produced via the purine metabolism pathway, and an abnormal level of uric acid could lead to serious diseases and complications, such as gout, renal, and cardiovascular diseases. A rapid, convenient, and accurate detection of uric acid is highly desired for healthcare applications. Here, we report a screen-printed amperometric biosensor for uric acid based on a composite ink consisting of graphene, Prussian blue (PB), and rhodium (Rh)/carbon catalyst. The working electrode is printed by a graphene/PB ink and an Rh/carbon (Rh/C) ink sequentially with drying in between. The linear detection range for uric acid is 0.040,8 mM with a response time of 30 s and a detection limit of 0.55 mu M The biosensor could be stored in a refrigerator at 4 C for 80 days without a significant decrease in response. Furthermore, compared to the detection results from the clinical standard method, the relative error of the biosensor is within 20% for detecting uric acid in human blood samples. It is anticipated that this work could advance exciting fundamental studies for uric acid-sensing devices, as well as the clinical applications for the detection of uric acid.