• 文献标题:   Graphene-based protein biomarker detection
  • 文献类型:   Review
  • 作  者:   PATIL AV, FERNANDES FB, BUENO PR, DAVIS JJ
  • 作者关键词:  
  • 出版物名称:   BIOANALYSIS
  • ISSN:   1757-6180 EI 1757-6199
  • 通讯作者地址:   Univ Oxford
  • 被引频次:   14
  • DOI:   10.4155/bio.15.4
  • 出版年:   2015

▎ 摘  要

An ability to detect and quantify protein molecules, harbingers of specific pathologies, potentially underpins both early disease diagnosis and an assessment of treatment efficacy. However, the specific detection of a particular protein biomarker in a complex environment is by no means an easy task and requires a progressive improvement in sensor technology. The high surface area, volume, electrical conductance, atomic level thickness and apparent biocompatibility of graphene makes it potentially an exceedingly powerful transducer of biorecognition events; the demands of its application in biosensing, and progress to date are reviewed herein.