• 文献标题:   Antibacterial Property of Graphene Quantum Dots (Both Source Material and Bacterial Shape Matter)
  • 文献类型:   Article
  • 作  者:   HUI LW, HUANG JL, CHEN GX, ZHU YW, YANG LH
  • 作者关键词:   twodimensional material, drugresistance, antimicrobial, fullerene, cytotoxicity
  • 出版物名称:   ACS APPLIED MATERIALS INTERFACES
  • ISSN:   1944-8244
  • 通讯作者地址:   Univ Sci Technol China
  • 被引频次:   38
  • DOI:   10.1021/acsami.5b10132
  • 出版年:   2016

▎ 摘  要

Whereas diverse graphene quantum dots (GQDs) with basal planes similar to those of graphene oxide sheets (i.e., GO-GQDs) lack antibacterial property, that prepared by rupturing C-60 cage (i.e., C-60-GQD) effectively kills Staphylococcus aureus, including its antibiotic-tolerant persisters, but not Bacillus subtilis, Escherichia coli, or Pseudomonas aeruginosa. The observed activity may correlate with a GQDs ability to disrupt bacterial cell envelop. Surface-Gaussian-curvature match between a GQD and a target bacterium may play critical role in the association of the GQD with bacterial cell surface, the initial step for cell envelope disruption, suggesting the importance of both GQDs source materials and bacterial shape.