▎ 摘　　要

This work demonstrates the facile and efficient preparation protocol of beta-Cyclodextrin-reduced graphene oxide modified glassy carbon electrode (beta-CD/RGO/GCE) sensor for an impressive chiral selectivity analysis for phenylalanine enantiomers. In this work, the immobilization of beta-CD over graphene sheets allows the excellent enantiomer recognition due to the large surface area and high conductivity of graphene sheets and extraordinary supramolecular (host-guest interaction) property of beta-CD. The proposed sensor was well characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FI'IR), and electrochemical impedance spectroscopy (EIS) techniques. The analytical studies demonstrated that the 13 -CD/ RGO/GCE exhibit superior chiral recognition toward L-phenylalanine as compared to n-phenylalanine. Under optimum conditions, the developed sensor displayed a good linear range from 0.4 to 40 mu M with the limit of detection (LOD) values of 0.10 mu M and 0.15 mu M for L- and D-phenylalanine, respectively. Furthermore, the proposed sensor exhibits good stability and regeneration capacity. Thus, the as-synthesized material can be exploited for electrochemical enantiomer recognition successfully.