• 文献标题:   A new composite scaffold of bioactive glass nanoparticles/graphene: Synchronous improvements of cytocompatibility and mechanical property
  • 文献类型:   Article
  • 作  者:   FAN ZJ, WANG JQ, LIU FZ, NIE YY, REN LL, LIU B
  • 作者关键词:   graphene, bioactive glas, scaffold, hydroxyapatite, mechanical property
  • 出版物名称:   COLLOIDS SURFACES BBIOINTERFACES
  • ISSN:   0927-7765 EI 1873-4367
  • 通讯作者地址:   Lanzhou Univ
  • 被引频次:   11
  • DOI:   10.1016/j.colsurfb.2016.05.026
  • 出版年:   2016

▎ 摘  要

This study presents a simple method of synthesizing bioactive glass nanoparticles/graphene nanosheets composite (BGs/GNS) scaffolds using the sol-gel and mold-compressing strategies. Characterizations of BGs/GNS scaffold revealed that BGs with an average diameter of 28.75 nm were densely anchored onto both sides of GNS. When the mass ratio of BGs to graphene oxide was set as 10, this scaffold showed better cytocompatibility and higher osseointegration ability with surrounding tissues than the other scaffolds. The introduction of GNS also significantly enhanced the hardness and Young's modulus of BGs. Given the excellent performance of this scaffold, it has potential applications in bone regeneration and implantation. (C) 2016 Elsevier B.V. All rights reserved.