• 文献标题:   Preparation of Graphene Quantum Dots and Their Biological Applications
  • 文献类型:   Review
  • 作  者:   SUN XD, LIU ZQ, YAN H
  • 作者关键词:   graphene quantum dot, morphology size control, synthetic method, biological application, review
  • 出版物名称:   JOURNAL OF INORGANIC MATERIALS
  • ISSN:   1000-324X
  • 通讯作者地址:   Tsinghua Univ
  • 被引频次:   8
  • DOI:  
  • 出版年:   2016

▎ 摘  要

As the derivatives of graphene, graphene quantum dots (GQDs) have the excellent properties of graphene, and photoluminescence (PL) properties that ordinary graphene does not possess, which is attributed to quantum confinement effect and boundary effect. Moreover, GQDs perform well in terms of cytotoxicity and biocompatibility. Recently, the synthetic method of GQDs is increasingly diverse, which is usually divided into two main groups: top-down and bottom-up. With increasing application of GQDs in biomedical field, higher requirements on their morphology and size control are put forward. In this paper, we focus on the synthetic methods that are promising to control morphology and size of GQDs. Advantages and disadvantages of these methods are listed and analyzed comparatively. The biological applications of GQDs, including biological imaging, biological sensors, drug delivery and antibacterial agents, etc. are introduced. Suggestions on the choice of synthetic method for preparation of GQDs are given based on the requirements of diverse applications. The remained problems and the development directions in the research of GQDs are put forward.