• 文献标题:   A new view of graphene oxide biosafety in a water environment using an eatable fish as a model
  • 文献类型:   Article
  • 作  者:   MA KY, ZHANG SP, YE BQ, OUYANG JY, YUE GH
  • 作者关键词:  
  • 出版物名称:   RSC ADVANCES
  • ISSN:   2046-2069
  • 通讯作者地址:   Natl Univ Singapore
  • 被引频次:   3
  • DOI:   10.1039/c5ra26026d
  • 出版年:   2016

▎ 摘  要

A comprehensive evaluation on the biosafety of graphene oxide (GO) was developed by combining 16S rRNA sequencing, gene expression detection, histology and a scanning electron microscope assay on fish. GO does not affect the diversity and composition of gut microbiota, but down-regulates gene expression in fish liver, suggesting that it poses a potential risk to aquatic ecosystems.