• 文献标题:   Graphene oxide-modified ZnO particles: synthesis, characterization, and antibacterial properties
  • 文献类型:   Article
  • 作  者:   ZHONG LL, YUN K
  • 作者关键词:   graphene oxide, zno, characterization, antibacterial property
  • 出版物名称:   INTERNATIONAL JOURNAL OF NANOMEDICINE
  • ISSN:   1178-2013
  • 通讯作者地址:   Gachon Univ
  • 被引频次:   68
  • DOI:   10.2147/IJN.S88319
  • 出版年:   2015

▎ 摘  要

Nanosized ZnO particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. The synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. The morphology of the graphene oxide sheets and ZnO particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. Fourier transform infrared spectroscopy and X-ray diffraction were used to analyze the physical and chemical properties of the ZnO/graphene oxide composites that differed from those of the individual components. Enhanced electrochemical properties were detected with cyclic voltammetry, with a redox peak of the composites at 0.025 mV. Excellent antibacterial activity of ZnO/graphene oxide composites was observed with a microdilution method in which minimum inhibitory concentrations of 6.25 mu g/mL for Escherichia coli and Salmonella typhimurium, 12.5 mu g/mL for Bacillus subtilis, and 25 mu g/mL for Enterococcus faecalis. After further study of the antibacterial mechanism, we concluded that a vast number of reactive oxygen species formed on the surface of composites, improving antibacterial properties.