▎ 摘　　要

Acid-base bifunctional catalysts are of particularly interest, but also present great challenges in synthesis and applications. In this study, acid-base bifunctional graphene oxide hybrids were obtained by the modification of graphene oxide (GO) through a silylation reaction and radical addition. The obtained bifunctional hybrids displayed high acid and base catalytic activities towards a typical one-pot acid-base reaction sequence called deacetalization-nitroaldol reaction.