• 文献标题:   A modified calcium silicate composite bone cement prepared from polyethylene glycol and graphene oxide for biomaterials
  • 文献类型:   Article
  • 作  者:   SHA S, QIU F, LI S, LIU JX, XU H, TANG J, ZHANG Y
  • 作者关键词:   vateritetricalcium silicate, graphene oxide, composite bone cement, biomaterial
  • 出版物名称:   MATERIALS TODAY COMMUNICATIONS
  • ISSN:  
  • 通讯作者地址:  
  • 被引频次:   7
  • DOI:   10.1016/j.mtcomm.2021.102431 EA MAY 2021
  • 出版年:   2021

▎ 摘  要

Polyethylene glycol modified graphene oxide (PEG-GO) will greatly improve the properties of tricalcium silicate containing vaterite (V-C3S) including compressive strength, in vitro mineralization ability, and cell compatibility and so on. Composite bone cement can improve some defects of calcium silicate biological bone material such as poor mechanical properties and lower cell activity. The results show that PEG-GO/V-C3S has satisfying curing ability, mechanical properties and high injectability. The compressive strength of composite bone cement has been improved significantly (35.24 % higher than that of pure V-C3S) and the pH environment is also better, so V-C3S containing 0.9 g/1 PEG-GO has better performance. Its extraordinary mineralization ability can be reflected in vitro immersion experiments. Cell experiments confirmed that compared with V-C3S and GO/V-C3S, it has lower cytotoxicity and higher cell proliferation ability. These results show that PEG-GO/V-C3S bone cement is a up-and coming material for biomaterials.