• 文献标题:   Monitoring bound HA1(H1N1) and HA1(H5N1) on freely suspended graphene over plasmonic platforms with infrared spectroscopy
  • 文献类型:   Article
  • 作  者:   BANERJEE A, CHAKRABORTY S, ALTANBONNET N, GREBEL H
  • 作者关键词:  
  • 出版物名称:   CHEMICAL PHYSICS LETTERS
  • ISSN:   0009-2614
  • 通讯作者地址:   New Jersey Inst Technol
  • 被引频次:   0
  • DOI:   10.1016/j.cplett.2013.07.010
  • 出版年:   2013

▎ 摘  要

Infrared (IR) spectroscopy provides fingerprinting of the energy and orientation of molecular bonds. The IR signals are generally weak and require amplification. Here we present a new plasmonic platform, made of freely suspended graphene, which was coating periodic metal structures. Only monolayer thick films were needed for a fast signal recording. We demonstrated unique IR absorption signals of bound proteins: these were the hemagglutinin area (HA1) of swine influenza (Hi NI) and the avian influenza (H5N1) viruses bound to their respective tri-saccharides ligand receptors. The simplicity and sensitivity of such approach may find applications in fast monitoring of binding events. (C) 2013 Elsevier B.V. All rights reserved.