▎ 摘　　要

Graphene shows great potential in biosensing and bioelectronics. To facilitate graphene's applications and enhance its performance, recently, three-dimensional (3D) graphene-based materials especially freestanding porous graphene with tunable pore size and void space, have attracted increasing attention for bio-related applications owing to their special features. 3D graphene usually shows the following merits such as an interconnected porous network, a high electronic conductivity, a large active surface area, good chemical/thermal stability and can be more easily handled compared with dispersed graphene sheets. With modified surface properties, graphene can also be bio-friendly. These properties make 3D graphene a perfect candidate as high-performance electrode materials in bioelectronics devices. In this review, we discuss recent advance in fabricating monolithic 3D graphene and their applications in biosensing and biofuel cells. (C) 2015 Elsevier B.V. All rights reserved.