• 文献标题:   Graphene- and Graphene Oxide-Based Nanocomposite Platforms for Electrochemical Biosensing Applications
  • 文献类型:   Review
  • 作  者:   THANGAMUTHU M, HSIEH KY, KUMAR PV, CHEN GY
  • 作者关键词:   graphene, graphene oxide, reduced graphene oxide, electrochemical biosensor, cell capture
  • 出版物名称:   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
  • ISSN:   1422-0067
  • 通讯作者地址:   Natl Chiao Tung Univ
  • 被引频次:   18
  • DOI:   10.3390/ijms20122975
  • 出版年:   2019

▎ 摘  要

Graphene and its derivatives such as graphene oxide (GO) and reduced GO (rGO) offer excellent electrical, mechanical and electrochemical properties. Further, due to the presence of high surface area, and a rich oxygen and defect framework, they are able to form nanocomposites with metal/semiconductor nanoparticles, metal oxides, quantum dots and polymers. Such nanocomposites are becoming increasingly useful as electrochemical biosensing platforms. In this review, we present a brief introduction on the aforementioned graphene derivatives, and discuss their synthetic strategies and structure-property relationships important for biosensing. We then highlight different nanocomposite platforms that have been developed for electrochemical biosensing, introducing enzymatic biosensors, followed by non-enzymatic biosensors and immunosensors. Additionally, we briefly discuss their role in the emerging field of biomedical cell capture. Finally, a brief outlook on these topics is presented.