▎ 摘　　要

The urease membrane was immobilized on the surface of indium gallium zinc oxide (IGZO) based on polyethylene terephthalate substrate, which was used to develop an arrayed flexible urea biosensor in this study. In order to improve the properties of arrayed flexible IGZO/Al urea biosensor, graphene oxide (GO) was employed to modify the properties of arrayed flexible IGZO urea biosensor. Compared with the average sensitivity of 1.53 mV/(mg/dl) and linearity of 0.931 for arrayed flexible IGZO/Al urea biosensor, the average sensitivity and linearity of arrayed flexible IGZO urea biosensor modified by GO achieved 3.06 mV/(mg/dl) and 0.970, respectively. As the result, 5 mM pH 7.0 PBS buffer solution was the optimal measurement environment for Urease/IGZO/GO/Al urea biosensor, and which the average sensitivity was 3.65 [mV/(mg/dl)]. Anti-interference testing showed the arrayed flexible IGZO/Al urea biosensor modified by GO was not easily interfered from the other materials.