• 文献标题:   Facile synthesis of ultrathin two-dimensional graphene-like CeO2-TiO(2)mesoporous nanosheet loaded with Ag nanoparticles for non-enzymatic electrochemical detection of superoxide anions in HepG2 cells
  • 文献类型:   Article
  • 作  者:   WANG ZX, ZHAO HL, GAO QM, CHEN KC, LAN MB
  • 作者关键词:   twodimensional, metal oxide, ag nanoparticle, superoxide anion, electrocatalytic reduction
  • 出版物名称:   BIOSENSORS BIOELECTRONICS
  • ISSN:   0956-5663 EI 1873-4235
  • 通讯作者地址:  
  • 被引频次:   14
  • DOI:   10.1016/j.bios.2021.113236 EA APR 2021
  • 出版年:   2021

▎ 摘  要

Here we presented a new facile strategy to fabricate ultrathin two-dimensional (2D) metal oxide nanosheets, by using polydopamine-coated graphene (rGO@PDA) as a template under simplywet-chemicalconditions. Based on the strategy, graphene-like CeO2-TiO(2)mesoporousnanosheet (MNS-CeO2-TiO2) was prepared and was loaded with dispersive Ag nanoparticles (AgNPs) to obtain effective electrocatalysts (denoted asAg/MNS-CeO2-TiO2) forelectrochemical detectionof superoxide anion (O-2(center dot & minus;)). Characterizations demonstrated that MNS-CeO2-TiO(2)exhibited ultrathin thickness, larger specific surface area, andpore volumein comparison with its bulk counterpart. The above properties of MNS-CeO2-TiO(2)shorten electron transmission distance, promotes mass transfer, and is conducive to the dispersion of post-modified AgNPs. Therefore, the recommended Ag/MNS-CeO2-TiO(2)sensors (denoted asAg/MNS-CeO2-TiO2/SPCE) exhibited satisfactory properties, including the sensitivity of 737.1 mu Acm(& minus;2)mM(& minus;1), the detection limit of 0.0879 mu M (S/N=3), and good selectivity. Meanwhile, the sensors also successfully realized in the online monitoring of O(2)(center dot & minus;)released from HepG2 cells, meaning the prepared sensors had practical application potential towards the analysis of O(2)(center dot & minus;)in biological samples.