• 文献标题:   A sonochemical synthesis of SrTiO3 supported N-doped graphene oxide as a highly efficient electrocatalyst for electrochemical reduction of a chemotherapeutic drug
  • 文献类型:   Article
  • 作  者:   RAJAJI U, RAGHU MS, KUMAR KY, ALMUTAIRI TM, MOHAMMED AA, JUANG RS, LIU TY
  • 作者关键词:   sonochemical synthesi, strontium titanate, n doped graphene oxide, nilutamide drug, laserinduced graphene electrode, biological fluids analysi
  • 出版物名称:   ULTRASONICS SONOCHEMISTRY
  • ISSN:   1350-4177 EI 1873-2828
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1016/j.ultsonch.2023.106293 EA JAN 2023
  • 出版年:   2023

▎ 摘  要

A sonochemical based green synthesis method playa powerful role in nanomaterials and composite development. In this work, we developed a perovskite type of strontium titanate via sonochemical process. SrTiO3 particles were incorporated with nitrogen doped graphene oxide through simple ultrasonic irradiation method. The SrTiO3/NGO was characterized by various analytical methods. The nanocomposite of SrTiO3/NGO was modified with laser-induced graphene electrode (LIGE). The SrTiO3/NGO/LIGE was applied for electrochemical sensor towards chemotherapeutic drug detection (nilutamide). Cyclic voltammetry (CV) and differential pulse vol-tammetry (DPV) techniques have been used to examine the electrochemical performance of nilutamide (anti-cancer drug). DPV was found to be more sensitive and found to exhibit a sensitivity 8.627 mu A mu M-1 cm-2 for SrTiO3/NGO/LIGE with a wide linear range (0.02-892 mu M) and low Limit of detection (LOD: 1.16 mu M). SrTiO3/ NGO/LIGE has been examined for the detection of nilutamide in blood serum and urine samples and obtained a good recovery in the range of 97.2-99.72 %. The enhanced stability and selectivity and practical application results indicates the suitability of SrTiO3/NGO/LIGE towards the detection of nilutamide drug in pharmaceutical industries.