▎ 摘　　要

NOVELTY - Composition of three-dimensional membranous surface-enhanced Raman spectroscopy (SERS) nanoprobe, is claimed. The composite nanomaterial has a three-dimensional structure with a uniform gold shell coated on the surface of a single-layer graphene oxide sheet as a two-dimensional SERS platform, a precisely controlled polyethyleneimine (PEI) interlayer as a built-in nanogap, and many externally assembled colloidal silver nanoparticles provides larger surface area and multiple SERS hotspots. The three-dimensional membranous SERS nanoprobe (graphene oxide/gold/silver) has excellent stability, monodispersity, excellent SERS activity and huge reaction interface. The graphene oxide/gold/silver composite nanomaterial is applied to the SERS immunochromatography system as a high-performance SERS probe. USE - The composition of three-dimensional membranous SERS nanoprobe is useful for SERS immunochromatography system (claimed). ADVANTAGE - The three-dimensional membranous SERS nanoprobe has good dispersion and excellent SERS activity, and can realize the ultrasensitive quantitative detection of the target in the immunochromatography system. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for preparing three-dimensional membranous SERS nanoprobe. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic diagram of a method for preparing a three-dimensional membranous SERS nanoprobe.