▎ 摘 要
NOVELTY - Dental coating composition comprises mixed solution of water and N-methyl-2-pyrrolidone, where the composition has N-methyl-2-pyrrolidone concentration of 0.1-20 %mass, and dispersion liquid of graphene oxide particles dispersed in the mixed solution of water and N-methyl-2-pyrrolidone. The dental coating composition is coated on tooth surface. USE - The dental coating composition e.g. dentifrice composition or cleaning composition is useful for controlling intraoral microorganisms chosen from Streptococcus mutans, S.sobrinus, Lactobacillus, Porphyromonas gingivali, Tannerella forsythia, Prevotella intermedia, Treponema denticola, Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Spirochetes, Fusobacterium and Candida albicans, and preventing dental caries and/or periodontal disease (all claimed). ADVANTAGE - The composition exhibits antimicrobial property with respect to intraoral areas for long period of time, and high invasiveness with respect to biological body and durability.