• 专利标题:   Dental coating composition e.g. dentifrice composition useful for e.g. controlling intraoral microorganisms, comprises mixed solution of water and N-methyl-2-pyrrolidone, and dispersion liquid of graphene oxide particles.
  • 专利号:   JP2016074636-A
  • 发明人:   MIYAJI H, TANAKA S, KAWANAMI M, SHINKAI M, MIMURA K
  • 专利权人:   UNIV HOKKAIDO, MITSUBISHI GAS CHEM CO INC
  • 国际专利分类:   A61K033/44, A61K047/22, A61K008/04, A61K008/19, A61K008/49, A61K009/10, A61P001/02, A61P031/04, A61Q011/00
  • 专利详细信息:   JP2016074636-A 12 May 2016 A61K-033/44 201637 Pages: 49 English
  • 申请详细信息:   JP2016074636-A JP206954 08 Oct 2014
  • 优先权号:   JP206954

▎ 摘  要

NOVELTY - Dental coating composition comprises mixed solution of water and N-methyl-2-pyrrolidone, where the composition has N-methyl-2-pyrrolidone concentration of 0.1-20 %mass, and dispersion liquid of graphene oxide particles dispersed in the mixed solution of water and N-methyl-2-pyrrolidone. The dental coating composition is coated on tooth surface. USE - The dental coating composition e.g. dentifrice composition or cleaning composition is useful for controlling intraoral microorganisms chosen from Streptococcus mutans, S.sobrinus, Lactobacillus, Porphyromonas gingivali, Tannerella forsythia, Prevotella intermedia, Treponema denticola, Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Spirochetes, Fusobacterium and Candida albicans, and preventing dental caries and/or periodontal disease (all claimed). ADVANTAGE - The composition exhibits antimicrobial property with respect to intraoral areas for long period of time, and high invasiveness with respect to biological body and durability.