▎ 摘 要
NOVELTY - The method involves dropping a DNA solution containing magnetic particles to a substrate. The magnetic particles are driven to move by using magnetic control. Single molecule DNA adsorbed on the substrate is stretched in the process of moving the DNA droplets. USE - Magnetic control molecular comb method for stretching single molecule DNA used in biological science and medical application e.g. gene filter base methylation analysis, DNA-protein interaction analysis and DNA damage detection. ADVANTAGE - The method has less DNA sample demand, convenient operation, high stretching rate, good stretching uniformity, and convenient for DNA sample processing and detection link integration.