• 专利标题:   Magnetic control molecular comb method for stretching single molecule DNA used e.g. in biological science, involves dropping DNA solution containing magnetic particles to substrate, driving magnetic particles to move and stretching single molecule DNA adsorbed on substrate.
  • 专利号:   CN113514297-A
  • 发明人:   FENG C, XU J, YU D, FU T, LIU W, CHEN Z, LIN Y, QIU R, LIN S, WU S
  • 专利权人:   UNIV FUJIAN AGRIC FORESTRY
  • 国际专利分类:   G01N001/28, G01N021/64
  • 专利详细信息:   CN113514297-A 19 Oct 2021 G01N-001/28 202210 Chinese
  • 申请详细信息:   CN113514297-A CN10683152 21 Jun 2021
  • 优先权号:   CN10683152

▎ 摘  要

NOVELTY - The method involves dropping a DNA solution containing magnetic particles to a substrate. The magnetic particles are driven to move by using magnetic control. Single molecule DNA adsorbed on the substrate is stretched in the process of moving the DNA droplets. USE - Magnetic control molecular comb method for stretching single molecule DNA used in biological science and medical application e.g. gene filter base methylation analysis, DNA-protein interaction analysis and DNA damage detection. ADVANTAGE - The method has less DNA sample demand, convenient operation, high stretching rate, good stretching uniformity, and convenient for DNA sample processing and detection link integration.