▎ 摘 要
NOVELTY - Mass-electrometry chip comprises an array of transistors, each comprising of a channel between two electrodes with a gate contact to modulate the electronic response of the channel, and an electrophoresis or focusing gel comprising gel-separated proteins, where the chip is configured so that the array provides a digital signal readout for fast multi-characteristic profiling and/or label-free identification of the proteins. The chip comprises liquid gated field effect transistors in a facile and miniaturized electrophoresis system configured to identify and measure the levels of proteins, based on their molecular weight and charge that are with molecular precision, digitally and in real-time. The gel is configured with distinct isoelectric focusing and gel electrophoresis areas, and the gel overlays the array, where the chip is configured to provide direct digital label-free identification, characterization and quantification of the proteins and real-time instantaneous fine resolution. USE - Mass-electrometry chip. ADVANTAGE - The mass-electrometry chip reduces the assay time and required starting sample, improves the accuracy and dynamic range of detection. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for using the chip.