▎ 摘　　要

NOVELTY - Sensor comprises a polymer layer (104) molecularly imprinted for an analyte (120), metal layer (108), electrocatalytic layer (106) disposed between the polymer layer and the metal layer, the electrocatalytic layer functionalized with at least one chemical compound that provides for noncovalent interaction with the analyte, and electrodes in operative arrangement with the polymer layer and configured to provide a signal indicative of a resistance. USE - The sensor is useful for: detecting analytes. e.g. viruses i.e. SARS-CoV-2, SARS2, SARS1, SARS-D614D, SARS-D614G, and/or Ebola from samples i.e. droplets or aerosols from exhaled breath (all claimed). ADVANTAGE - The sensor is rapid, non-invasive, and provides specific detection of viral infection. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for (1) detector comprising the sensor, and a voltage source configured to apply a voltage to the polymer layer; (2) method (M1) of detecting an analyte, comprising measuring a resistance of a molecularly imprinted polymer exposed to a sample, the molecularly imprinted polymer imprinted for the analyte and in operative arrangement with an electrocatalyst and a metal, the electrocatalyst functionalized with at least one chemical compound that provides for noncovalent interaction with the analyte, the electrocatalyst disposed between the molecularly imprinted polymer and the metal, the measured resistance indicative of a presence of the analyte in the sample; (3) method (M2) of detecting an analyte, comprising exposing the detector to a sample, and measuring the resistance of the device as the polymer layer is exposed to the sample to obtain a measured resistance, where the measured resistance is indicative of a presence of the analyte in the sample; (4) method (M3) of detecting a viral infection in a subject comprising exposing the sensor to a sample obtained from the subject, where the analyte is a receptor-binding domain of a virus, and measuring the resistance of the device as the polymer layer is exposed to the biological sample to obtain a measured resistance, where the measured resistance is indicative of the viral infection in the subject; and (5) method (M4) of manufacturing a sensor comprising depositing an electrocatalytic layer onto a metal layer, functionalizing the electrocatalytic layer with at least one chemical compound that provides for noncovalent interaction with an analyte of interest, and forming a molecularly imprinted polymer on the electrocatalytic layer, the molecularly imprinted polymer imprinted for the analyte. DESCRIPTION OF DRAWING(S) - The figure shows schematic representation of sensor. Polymer layer (104) Electrocatalytic layer (106) Metal layer (108) Analyte (120)