▎ 摘　　要

NOVELTY - Manganese dioxide targeted nano-drug carrier, where the carrier of the drug carrier is manganese dioxide-polydopamine-folic acid (MnO2-PDA-FA), the carrier has a spherical structure, PDA is modified on the surface of MnO2, and then PDA and FA are connected through an amide bond and the drug loaded by the nano drug carrier is glucose oxidase and camptothecin (CPT). USE - Used as manganese dioxide targeted nano-drug carrier. ADVANTAGE - The manganese dioxide targeted nano-medicine carrier is useful in in the field of biomedicine to load anti-cancer drugs (claimed). DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) preparing manganese dioxide targeted nano-drug carrier of the MnO2-PDA-FA comprises (1) dispersing the hydrochloric acid solution and potassium permanganate (KMnO4) powder in ultrapure water, stirring and pouring into the reaction kettle for reaction, (2) centrifuging the reaction liquid to remove the supernatant, re-suspending the precipitate with ultra-pure water, centrifuging to remove the supernatant, re-suspending the precipitate with absolute ethyl alcohol, centrifuging to remove the supernatant, re-suspending the precipitate with a small amount of ultra-pure water, drying to obtain the nano manganese dioxide, (3) dissolving MnO2 in ultra-pure water, ultrasonically processing to completely dissolve, adding quantitative DA in the MnO2 suspension, stirring and mixing uniformly, concentration is 10% of concentrated aqueous ammonia to adjust the pH, stirring to obtain MnO2-PDA, adding quantitative FA in the reaction liquid, continuously stirring in dark place, (4) adding the reaction liquid in the dialysis bag, using ultra-pure water for dialysis to remove the unconnected precursor molecule, precipitating with a small amount of ultra-pure water re-suspending, freezing and drying to obtain MnO2-PDA-FA; and (2) preparing manganese dioxide targeting nano drug carrier load medicine comprising dispersing of MnO2-PDA-FA in ultra-pure water, adding graphene oxide (GOX), stirring and reacting at 37 degrees C, to obtain MnO2-PDA-FA + GOX, adding camptothecin (CPT) in the MnO2-PDA-FA+ GOX solution, stirring and reacting at room temperature to obtain MnO2-PDA-FA+GOX+CPT.