• 专利标题:   Preparing graphene quantum dot used in e.g. detecting water content in organic solvents comprises adding pyrene into concentrated nitric acid, refluxing, dissolving e.g. dry trinitropyrene in ethanol, filtering, purifying and drying.
  • 专利号:   CN110540192-A
  • 发明人:   SHEN L, GENG B, PAN D
  • 专利权人:   SHANGHAI SIXTH PEOPLES HOSPITAL
  • 国际专利分类:   B82Y030/00, B82Y040/00, C01B032/184, C09K011/65
  • 专利详细信息:   CN110540192-A 06 Dec 2019 C01B-032/184 201998 Pages: 11 Chinese
  • 申请详细信息:   CN110540192-A CN10858322 11 Sep 2019
  • 优先权号:   CN10858322

▎ 摘  要

NOVELTY - Preparing graphene quantum dot comprises adding pyrene into concentrated nitric acid (65 wt.%), condensing and refluxing at 80 degrees C for 24-48 hours, cooling to room temperature, adding excess deionized water and performing suction filtration using a filter membrane, adding deionized water repeatedly, filtering and washing until the pH is neutral, placing the reaction product in an vacuum oven and drying at 65-85 degrees C to obtain yellow powder of trinitropyrene, (ii) weighing and dissolving dry trinitropyrene and sodium sulfite in ethanol, stirring uniformly, transferring the solution to a polytetrafluoroethylene based reaction kettle, reacting at 180-210 degrees C for 10-12 hours and (iii) completing the high-temperature reaction, cooling to room temperature, filtering the reaction product using 0.22 mu m filter membrane to remove unreacted particles, purifying using column chromatography separation and drying to obtain the product. USE - The quantum dot is useful in detecting water content in organic solvents and cell imaging based on fluorescence changes. ADVANTAGE - The quantum dot: is hydrophobic.