• 专利标题:   Implantable electrode used to record and stimulate peripheral nerve, comprises multi-layer graphene-fiber core, insulative coating surrounding multi-layer graphene-fiber core and metal layer.
  • 专利号:   US2020155834-A1, WO2020106986-A1
  • 发明人:   ROMEROORTEGA M, WALLACE G, GONZALEZ G M, JALILI R A, GONZALEZ GONZALEZ M
  • 专利权人:   UNIV TEXAS SYSTEM, UNIV WOLLONGONG, UNIV TEXAS SYSTEM, UNIV WOLLONGONG
  • 国际专利分类:   A61N001/05, C23C014/18, C23C014/34, B82Y030/00, B82Y040/00, C01B032/00, C01B032/182, H01G011/32, H01G011/36, H01G011/66, H01G011/68
  • 专利详细信息:   US2020155834-A1 21 May 2020 A61N-001/05 202046 Pages: 52 English
  • 申请详细信息:   US2020155834-A1 US691309 21 Nov 2019
  • 优先权号:   US770540P, US691309

▎ 摘  要

NOVELTY - Implantable electrode comprises: a multi-layer graphene-fiber core; an insulative coating surrounding the multi-layer graphene-fiber core; and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating. USE - The electrode is useful for recording and stimulating peripheral nerve (claimed). ADVANTAGE - The electrode: detects neuronal activity with improved signal to noise ratios when compared to conventional microelectrode arrays; and detects neuronal activity with a high signal to noise ratio. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are also included for: (1) making (M1) an implantable electrode comprising forming a multi-layered graphene-fiber core by performing an in-situ reduction of fully ordered graphene oxide sheets in a liquid crystalline, coating at least a portion of the multi-layered graphene-fiber core with a metal layer and coating the multi-layered graphene-fiber core and metal layer with an insulative coating; and (2) recording and stimulating (M2) a peripheral nerve, comprising exposing and isolating a target nerve from the surrounding tissue, engaging an implantable electrode to the target nerve by at least one of passing the implantable electrode about the exposed target nerve and forming a knot with implantable electrode, and inserting the implantable electrode through the epineurium of the exposed target nerve, where the implantable electrode further comprises a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating and at least one of recording and stimulating from the peripheral nerve.