• 专利标题:   Preparing magnetic microspheres useful for separating and purifying nucleic acid and/or protein, comprises e.g. preparing graphene oxide and ferric chloride by hydrothermal synthesis and modifying chitosan shell on surface.
  • 专利号:   CN115970654-A
  • 发明人:   XIE Y, LIU B, HUANG C, ZHONG Q
  • 专利权人:   YIBO XIAMEN TECHNOLOGY CO LTD
  • 国际专利分类:   B01D015/38, B01J020/24, B01J020/28, B01J020/32, C07K001/14, C07K014/765, C12N015/10
  • 专利详细信息:   CN115970654-A 18 Apr 2023 B01J-020/24 202345 Chinese
  • 申请详细信息:   CN115970654-A CN10113091 15 Feb 2023
  • 优先权号:   CN10113091

▎ 摘  要

NOVELTY - Preparing magnetic microspheres comprises (i) preparing graphene oxide and ferric chloride by hydrothermal synthesis to obtain magnetic core, and (ii) modifying chitosan shell on surface of magnetic core to obtain magnetic microspheres. USE - The method is useful in preparing magnetic microspheres for separating and purifying nucleic acid and/or protein (all claimed). ADVANTAGE - The method has high-efficacy. The magnetic microsphere has ≥96% recovery rate to nucleic acid, and ≥92% recovery rate to protein. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for use of magnetic microspheres for separating and purifying nucleic acid and/or protein.