▎ 摘　　要

NOVELTY - Preparing magnetic microspheres comprises (i) preparing graphene oxide and ferric chloride by hydrothermal synthesis to obtain magnetic core, and (ii) modifying chitosan shell on surface of magnetic core to obtain magnetic microspheres. USE - The method is useful in preparing magnetic microspheres for separating and purifying nucleic acid and/or protein (all claimed). ADVANTAGE - The method has high-efficacy. The magnetic microsphere has ≥96% recovery rate to nucleic acid, and ≥92% recovery rate to protein. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for use of magnetic microspheres for separating and purifying nucleic acid and/or protein.