• 专利标题:   Complex useful for producing prosthetic-type biomedical device, preferably 4D prosthetic-type biomedical device, comprises polylactic acid and graphene oxide.
  • 专利号:   WO2022162260-A1, ES2919782-A1
  • 发明人:   GONZALEZ FERNANDEZ P M, SERRA RODRIGUEZ J A, GONZALEZ RODRIGUEZ L, PEREZ DAVILA S, CHIUSSI S
  • 专利权人:   UNIV VIGO
  • 国际专利分类:   A61L027/46, A61L027/54, A61L031/12, A61L031/16, B33Y070/00, B33Y080/00, A61F002/02, A61L027/44, B29C064/10, B29C067/00, B33Y010/00, B33Y070/10
  • 专利详细信息:   WO2022162260-A1 04 Aug 2022 A61L-027/46 202271 Pages: 25 English
  • 申请详细信息:   WO2022162260-A1 WOES070033 25 Jan 2022
  • 优先权号:   ES000015

▎ 摘  要

NOVELTY - Complex comprises 69.98-98.99% polylactic acid (PLA) and 0.002-0.02% graphene oxide (GO). USE - The complex is useful for producing prosthetic-type biomedical device, preferably 4D prosthetic-type biomedical device (all claimed). ADVANTAGE - The complex has excellent biocompatibility, biodegradability, durability and bioavailability, can be manufactured in a cost-effective manner with high yield, reduces adverse effects of radiation ionizant on the patient's health, and prevents the patient from changing the implant every decade, which makes daily life easier without surgery. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: prosthetic-type biomedical device comprising the complex; method for producing the prosthetic-type biomedical device involves performing 3-dimensional (D) printing of biomedical device; method for modifying shape and/or size of the prosthetic-type biomedical device involves (a) providing the prosthetic-type biomedical device, and (b) irradiating the biomedical device with a laser or LED light; and method for producing a 4D prosthetic-type biomedical device involves (a) printing a prosthetic-type biomedical device by 3D printing, and irradiating the prosthetic-type biomedical device with a laser or LED light to modify its shape and/or size and/or for controlled release of at least one drug.