• 专利标题:   Use of hybrid nanoparticles, preferably highly reduced graphene oxide-manganese oxide, as photodynamic therapy agent for treating cancer and as contrast agent for imaging cancer cells.
  • 专利号:   US2022339300-A1
  • 发明人:   EKHZAIMY A A, ALRASHOOD S T, SHAIK M R, KHAN H A
  • 专利权人:   UNIV KING SAUD
  • 国际专利分类:   A61K041/00, A61K049/18, A61P035/00, C01B032/184, C01B032/198, C01B032/23, C01G045/02
  • 专利详细信息:   US2022339300-A1 27 Oct 2022 A61K-049/18 202294 English
  • 申请详细信息:   US2022339300-A1 US863066 12 Jul 2022
  • 优先权号:   US863066

▎ 摘  要

NOVELTY - Use of hybrid nanoparticles, preferably highly reduced graphene oxide (HRG)-manganese oxide as photodynamic therapy agent and imaging agent for cancer, is claimed. USE - Hybrid nanoparticles for use as photodynamic therapy agent for treating cancer and/or as contrast agent for imaging cancer cells (claimed). Test details are described but no results given. ADVANTAGE - The hybrid nanoparticles are biocompatible and do not cause cytotoxicity at normal physiological conditions. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for synthesis the hybrid nanoparticle, which involves: a. synthesising manganese oxide nanoparticles; b. synthesising highly reduced HRG nanoparticles; and c. preparing highly reduced HRG-manganese oxide hybrid nanoparticles by milling manganese oxide nanoparticles and highly reduced HRG nanoparticles.