• 专利标题:   Nanoparticle composition has graphene oxide nanoparticles (GO) that comprises multiple graphene sheets that having multiple carboxylic and hydroxyl groups and interconvertible open and closed forms, and open form having specific sizes , Nanoparticle composition has graphene oxide nanoparticles (GO) that comprises multiple graphene sheets that having multiple carboxylic and hydroxyl groups and interconvertible open and closed forms, and open form having specific sizes.
  • 专利号:   US2021221690-A1
  • 发明人:   SARKAR S, ALLAM A
  • 专利权人:   SINON THERAPEUTICS INC
  • 国际专利分类:   C01B032/23
  • 专利详细信息:   US2021221690-A1 22 Jul 2021 C01B-032/23 202177 English
  • 申请详细信息:   US2021221690-A1 US198716 11 Mar 2021
  • 优先权号:   US234252P, US198716

▎ 摘  要

NOVELTY - The composition has graphene oxide nanoparticles (GO) that comprises multiple graphene sheets that having multiple carboxylic and hydroxyl groups and interconvertible open and closed forms. The open form having a size of about 40 nm to 200 nm. The closed form having a diameter of about 2 nm to 120 nm. Where the open form can be converted to the closed form at a pH of about 6.8 or lower, and the closed form can be converted to the open form at a pH of about 7.2 or higher. USE - Nanoparticle composition. ADVANTAGE - The GO nanoparticles are believed to convert between the closed and open forms as a result of an epoxidediol inter-conversion. The elasticity of the blood vessel and the gradual enhancement in florescence due to the wsCNP clearly demonstrated the passage of the wsCNO along the blood vessel and into the brain. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) a method for reversible encapsulation of a molecule within the GO; and (2) a method for delivering a water-soluble carbon nanoparticle (wsCNP).