▎ 摘　　要

NOVELTY - Production of graphene oxide/graphene-modified photosensitizer nanocomposite material involves dissolving polyacrylic acid in aqueous ammonia, adding sensitizer photosan to form solution (A), adding butyl titanate to glacial acetic acid solution to form transparent solution (B), dripping solution (B) into solution (A), reacting, centrifuging, washing precipitate, drying to obtain titanium oxide nano-hollow sphere particles loaded with photosan, dissolving in solution (A), adding graphene oxide to anhydrous ethanol and dispersing to form transparent solution (C), uniformly mixing transparent solution (C) and phosphoric acid buffer solution to obtain mixed solution (D), reacting, washing, drying to obtain polystyrene-titanium dioxide-polystyrene nanocomposite particle photosensitizer, reacting, centrifuging, washing precipitate and drying. USE - Production of graphene oxide/graphene-modified photosensitizer nanocomposite material used in photodynamic therapy, and for preparing medicine for treating tumor caused by human esophageal cancer (Eca-109) cells (all claimed). ADVANTAGE - The method enables simple production of graphene oxide/graphene-modified photosensitizer nanocomposite material with excellent solubility, biocompatibility and synergistic effect for treating tumor, and low cytotoxicity.