▎ 摘　　要

NOVELTY - Preparing cobalt-metal-organic frameworks (Co-MOF)/chitosan/graphene oxide chiral composite material, comprises dissolving 1.8-2.2 g chitosan in mixed solution of 92-96 ml water and 3.0-3.4 ml 36% acetic acid, adding 3.4-3.8 g cobalt nitrate hexahydrate and 0.3-0.5 g graphene oxide, and stirring thoroughly to obtain gel, dissolving 1.8-2.2 g sodium hydroxide and 2.4-2.8 g 2-methylimidazole in 33-37 ml water, dripping 7.5-8.7 g red gel using a 0.3-0.5 mm diameter injection needle, immediately forming blue ball having diameter of 1.5-2 mm, reacting at 80 degrees C for overnight, filtering the reaction mixture, washing the obtained solid three times with ethanol and water to obtain final product. USE - The composite material is useful for electrochemical sensing detection of enantiomers (claimed). ADVANTAGE - The method: has simple process and low reaction energy consumption; utilizes low cost raw material. The composite material: utilizes simple detection process, which is easy to operate; and has remarkable chiral detection effect. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for use of the chiral composite material for electrochemical sensing detection of enantiomers, comprising polishing 4 mm glassy carbon electrode surface with alumina powder, washing with water and ethanol, drip-coating 6 mu l Co-MOF/chitosan/graphene oxide chiral composite material suspension and air-drying at room temperature to obtain working electrode of Co-MOF/chitosan/graphene oxide chiral sensor, where the Co-MOF/chitosan/graphene oxide chiral composite suspension is prepared by blending 3 mg Co-MOF/chitosan/graphene oxide chiral composite material with 250 mu l isopropanol, 720 mu l water, and 30 mu l nafion in a 180 W water bath for 10-15 minutes, (ii) constructing the working electrode of chiral electrochemical sensor, connecting saturated calomel reference electrode and platinum wire counter electrode to the electrochemical workstation to prepare Co-MOF/chitosan/graphene oxide composite chiral sensor, (iii) detecting L-tyrosine and D-tyrosine enantiomers using phosphate-buffered saline buffer solution having pH of 7 and 0.1 mol/l as electrolyte, Co-MOF/chitosan/graphene oxide composite material chiral sensor uses differential pulse voltammetry to measure the current values of different concentrations of L-tyrosine and D-tyrosine standard solutions, and draws draw the L-tyrosine and D-tyrosine enantiomer working curves based on Co-MOF/chitosan/graphite oxide composites, replacing the L-tyrosine and D-tyrosine standard solutions by the solution of the sample to be tested, and measuring the L-tyrosine and D-tyrosine content in the samples.