• 专利标题:   Controllable degradation bone implant composite material used in bone tissue repairing material, comprises nano bioglass material and amino acid polymer and modified calcium carbonate whisker/natural rubber latex composite with graphene.
  • 专利号:   CN111437440-A
  • 发明人:   INVENTOR U
  • 专利权人:   HANGZHOU LUYANG TECHNOLOGY CO LTD
  • 国际专利分类:   A61L027/02, A61L027/08, A61L027/10, A61L027/16, A61L027/18, A61L027/50, A61L027/58, A61L031/02, A61L031/04, A61L031/06, A61L031/14, C03B019/10, C03C012/00, C08G069/10
  • 专利详细信息:   CN111437440-A 24 Jul 2020 A61L-027/10 202068 Pages: 15 Chinese
  • 申请详细信息:   CN111437440-A CN10252722 02 Apr 2020
  • 优先权号:   CN10252722

▎ 摘  要

NOVELTY - Controllable degradation bone implant composite material comprises nano bioglass material and amino acid polymer as main body structure and modified calcium carbonate whisker/natural rubber latex composite as a synergistic component, where the graphene is added to the modified calcium carbonate whisker/natural rubber latex composite. USE - The bone implant composite material is useful in preparation of bone tissue repairing material (claimed). ADVANTAGE - The bone implant composite material has excellent biological activity and biocompatibility and sufficient mechanical strength, facilitates interaction between tissue and cells and materials, can be rapidly degraded in the later stage and has degradation rate that can be adjusted by changing the components to achieve controllable degradation. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the bone implant composite material involving dissolving epsilon -aminocaproic acid, arginine nonamer and other alpha -amino acids in deionized water, removing water under the protection of nitrogen, raising the temperature to 200-220 degrees C, reacting for 1-2 hours, raising the temperature to 230-235 degrees C, reacting for 1-2 hours, adding the nano bioglass material and the synergistic component, uniformly mixing and cooling to obtain the bone implant composite material.