• 专利标题:   Organic NIR-II light-to-heat conversion film useful in tumor photo-thermal treatment material, comprises hydrogen bond aggregation formed by the hydrogen bond interaction between 3,3',5,5'-tetramethylbenzidine oxide and agarose.
  • 专利号:   CN112336856-A, CN112336856-B
  • 发明人:   CHEN Z, XU J, YIN Z, ZHANG L, DONG Q
  • 专利权人:   UNIV HUNAN
  • 国际专利分类:   A61K041/00, A61K047/26, A61K009/70, A61P035/00
  • 专利详细信息:   CN112336856-A 09 Feb 2021 A61K-041/00 202129 Pages: 14 Chinese
  • 申请详细信息:   CN112336856-A CN10974648 16 Sep 2020
  • 优先权号:   CN10974648

▎ 摘  要

NOVELTY - Organic NIR-II light-to-heat conversion film comprises hydrogen bond aggregation formed by the hydrogen bond interaction between 3,3',5,5'-tetramethylbenzidine oxide and agarose. USE - The film is useful in tumor photo-thermal treatment material (claimed). ADVANTAGE - The film has good uniformity, stable property, excellent NIR-II photo-thermal conversion efficiency and initial heating rate of 30 degrees C/second. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing an organic NIR-II light-to-heat conversion film, comprising (a) carrying out oxidation reaction of the mother liquor of 3,3',5,5'-tetramethylbenzidine in the presence of nano-enzyme catalysis and buffer to obtain nano-enzyme/3,3',5 ,5'-Tetramethylbenzidine oxide composite solution, (b) mixing and heating the nanozyme/3,3',5,5'-tetramethylbenzidine oxide composite solution with agarose to obtain a sol, and (c) cooling the sol to obtain a first hydrogel, and the first hydrogel continues to undergo a catalytic oxidation reaction to obtain a second hydrogel and drying the second hydrogel.