• 专利标题:   Sensor for detecting biological molecule comprises graphene structure; two electric contacts arranged in contact with graphene structure; and linker attached to graphene structure, where graphene has binding affinity for biological molecule.
  • 专利号:   WO2011004136-A1, GB2471672-A, GB2471672-B
  • 发明人:   GUY O J
  • 专利权人:   UWS VENTURES LTD, SWANSEA INNOVATIONS LTD
  • 国际专利分类:   C12Q001/00, G01N027/00, G01N033/543, G01N027/04
  • 专利详细信息:   WO2011004136-A1 13 Jan 2011 C12Q-001/00 201109 Pages: 33 English
  • 申请详细信息:   WO2011004136-A1 WOGB001231 23 Jun 2010
  • 优先权号:   GB011705

▎ 摘  要

NOVELTY - A sensor for detecting the presence of at least one biological molecule, comprises: graphene structure (120), particularly patterned graphene structure; additionally at least two electric contacts (130) arranged in contact with the patterned graphene structure for determining a conductivity; and at least one linker attached to at least a portion of the patterned graphene structure, where at least a portion of the graphene structure is functionalized such that the functionalized portion of the graphene structure has a binding affinity for biological molecule. USE - As sensor for detecting the presence of at least one biological molecule (claimed). ADVANTAGE - The sensor is highly specific and sensitive. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: (1) detecting the presence of at least one biological molecule using the sensor, involving: measuring the conductivity between the two electrical contacts; exposing the sensor to an environment with the biological molecule such that the biological molecule binds to the linker; measuring a change in the conductivity, where the change in the conductivity is caused cause by the binding of the biological molecule; (2) functionalizing (m1) graphene, involving: providing a graphene surface; attaching at least one nitrobenzene molecule to the graphene surface; and reducing the nitrobenzene to an aniline; (3) producing (m2) a sensor for detecting biological molecules, involving growing a graphene structure on a silicon carbide substrate (110); functionalizing at least a portion of the graphene structure such that the portion of the graphene structure has a binding affinity for at least one biological molecule. DESCRIPTION OF DRAWING(S) - The figure shows a three-dimensional representation of a sensor comprising graphene nanochannel and nano-transitor devices. Silicon carbide substrate (110) Graphene structure (120) Electric contacts (130) Silicon dioxide layer (150)