• 专利标题:   Detecting or quantifying hypoxanthine in forensic investigation, by reacting hypoxanthine-containing sample with composition containing xanthine oxidase and chromogenic substrate, measuring degree of color development of composition by absorbance, and detecting or quantifying hypoxanthine.
  • 专利号:   KR2022141035-A
  • 发明人:   HYUNKYU P, KIM S, ZHU Y, JUNG H
  • 专利权人:   KOREA ADVANCED SCI TECHNOLOGY INST
  • 国际专利分类:   C12Q001/26, C12Q001/28, G01N021/31, G01N021/78, G01N033/487, G01N033/52
  • 专利详细信息:   KR2022141035-A 19 Oct 2022 G01N-021/78 202297 Pages: 10
  • 申请详细信息:   KR2022141035-A KR047071 12 Apr 2021
  • 优先权号:   KR047071

▎ 摘  要

NOVELTY - Method (M1) for detecting or quantifying hypoxanthine involves (a) reacting by adding a hypoxanthine-containing sample to a composition capable of detecting hypoxanthine containing xanthine oxidase, peroxidase or its analog and a chromogenic substrate, and (b) measuring the degree of color development of the composition to which the sample is added by absorbance, and detecting or quantifying hypoxanthine in the sample. USE - The method is useful for detecting or quantifying hypoxanthine, and measuring the elapsed time of cadaver (claimed), which is used in various fields including forensic investigation. ADVANTAGE - The method easily detects hypoxanthine with naked eye within a short period of time and without requiring expensive and large equipment, and uses simple analysis based on a color reaction signal. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for the following: composition comprising xanthine oxidase, peroxidase or its analog, and a chromogenic substrate as active ingredients; and method (M2) for determining the elapsed time of a cadaver involving performing the above-mentioned method (M1) and measuring the elapsed time of the cadaver after death, where the sample is body fluid.