▎ 摘　　要

NOVELTY - Method of preparing bacterial cellulose and graphene based vascular graft, comprises (a) obtaining bacterial cellulose from bacteria, (b) drying the bacterial cellulose by freeze drying method, (c) dissolving the dry sponge structure of the obtained cellulose in ionic liquids, (d) mixing until the cellulose is completely dissolved, and a clear mixture is formed, (e) keeping the solution at 50° C, (f) obtaining biological material, (g) preparing the bacterial cellulose solution, (h) preparing the solutions of graphene and/or graphene derivatives, and (i) three-dimensional (3D) printing of a graphene-doped and bacterial cellulose-based vascular graft. USE - The method is used for preparing bacterial cellulose and graphene based vascular graft for treatment of cardiovascular diseases and/or vascular surgery applications. No biological data is given. ADVANTAGE - The method can overcome the occlusion problem experienced in vessel grafts smaller than 6 mm in diameter by the bacterial cellulose in its structure. The method can improve the mechanical properties of the vascular graft and the cell adhesion characteristics of graphene and/or various graphene derivatives added to the vessel graft, in addition to these properties of bacterial cellulose. The obtained vascular graft does not experience occlusion problems even at smaller vessel diameters compared to existing synthetic vessels by the production of bacterial cellulose-based vessels, has higher biocompatibility, and has similar properties to the original vessel physical properties. The vascular graft is more natural, and does not contain polymers such as Teflon(RTM: PTFE) and polyethylene terephthalate, and is safer for human health compared to artificial vascular grafts. The method improves properties such as cell viability and physical strength of the vascular graft.