▎ 摘　　要

NOVELTY - A integrating signal based on photo-thermal effect of graphene oxide detection method involves pretreating the surface of the thermometer mercury head, inserting the treated thermometer mercury head into the antibody solution,incubating and washing, adding the target analyte antibody to the graphene oxide solution to obtain an antibody-graphene complex, that is, immunographene and detecting the target object. USE - Method for integrating signal detection based on the photothermal effect of graphene oxide, for detecting cancer cells, bacteria, macromolecular proteins and small molecule substances, where the bacteria is Salmonella, and the macromolecular proteins are allergens and carcinoembryonic antigens, and small molecular substances are residues of agricultural veterinary drugs (claimed). ADVANTAGE - The method enables detecting integrating signal with better sensitivity, in simple and cost effective manner.