• 专利标题:   Anti-tumor drug loaded nano system comprises anticancer drugs loaded on carboxyl graphene oxide nanoparticle connected to carboxyl tumor graphene oxide nanoparticle targeting molecules, prepared by graphene oxide carboxylation.
  • 专利号:   CN104436210-A
  • 发明人:   LI X, YANG Z, WEI L, ZHANG Y, LU D
  • 专利权人:   UNIV SHANGHAI JIAOTONG
  • 国际专利分类:   A61K031/585, A61K047/48
  • 专利详细信息:   CN104436210-A 25 Mar 2015 A61K-047/48 201538 Pages: 8 Chinese
  • 申请详细信息:   CN104436210-A CN10647649 14 Nov 2014
  • 优先权号:   CN10647649

▎ 摘  要

NOVELTY - Anti-tumor drug loaded nano system comprises anticancer drugs loaded on photothermal carboxyl graphene oxide nanoparticle connected to carboxyl tumor graphene oxide nanoparticle targeting molecules. USE - Anti-tumor drug loaded nano system used for treating lung cancer, liver cancer, stomach and spleen tumors, lymph cancer, breast cancer or prostate cancer cells (claimed). ADVANTAGE - The anti-tumor drug loaded nano system has good efficiency and simple preparation. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for the preparation of anti-tumor drug loaded nano system comprising performing carboxylation of graphene oxide, dispersing, adding carboxamide amine activator, connecting activator-mediated tumor targeting molecule in the carboxyl graphene oxide surface, and performing conjugation via pi-pi to obtain carboxyl graphene oxide carrying one or more anticancer drugs.