• 专利标题:   Preparing 2,4-dichloro-5-isopropoxyaniline involves using 2,4-dichloro-5-propoxynitrobenzene as raw material, and loading graphene with precious metal, and then carrying out reaction in presence of catalyst, reaction solvent i.e. water.
  • 专利号:   CN108689867-A
  • 发明人:   YANG J, CAO X, SUN J, SHI W, SUN P
  • 专利权人:   LIANYUNGANG JINDUN AGROCHEMICAL CO LTD
  • 国际专利分类:   C07C213/02, C07C217/84
  • 专利详细信息:   CN108689867-A 23 Oct 2018 C07C-213/02 201883 Pages: 5 Chinese
  • 申请详细信息:   CN108689867-A CN10273752 29 Mar 2018
  • 优先权号:   CN10273752

▎ 摘  要

NOVELTY - Preparing 2,4-dichloro-5-isopropoxyaniline involves using 2,4-dichloro-5-propoxynitrobenzene as a raw material, and loading graphene with precious metal, and then carrying out reaction in presence of a catalyst, reaction solvent i.e. water and a phase transfer catalyst i.e. crown ether at 1.5-3 MPa and 100-130 degrees C for 2-6 hours. The catalyst is recovered by pressure filtration. The reaction temperature is lowered to room temperature, and then centrifuged to obtain 2 ,4-dichloro-5-isopropoxyaniline. The crown ether is selected from 12-crown-4, 15-crown-5 or 18-crown-6. The molar ratio of phase transfer catalyst to starting material is 0.005-0.03:1. USE - Method for preparing 2,4-dichloro-5-isopropoxyaniline (claimed). ADVANTAGE - The method enables to prepare 2,4-dichloro-5-isopropoxyaniline more than 99.5% chromatographic purity, more than 95% yield improved quality in a simple and rapid manner, and significantly reduce amount of waste residue and waste water.