▎ 摘　　要

NOVELTY - Device comprises an artificial membrane on graphene with one or more apertures, where the artificial membrane comprises two lipid monolayers each contacting one face of the graphene, and the two lipid monolayers form a lipid bilayer within the apertures in the graphene. USE - The device is useful for analyzing a target polymer and for identifying a membrane molecule-interacting compound, where the membrane molecule is a transmembrane protein (all claimed). The device is useful: for detecting properties of polymers (e.g. sequence or length of a polynucleotide); for the study of organisms, preferably cells or viruses; for the study of interaction of compounds with lipids e.g. glycolipids, lipids conjugated to other compounds or other non-protein compounds in the bilayer; and for the study of the ability of compounds to pass through a lipid bilayer or monolayer, e.g. in transfection or drug delivery. ADVANTAGE - The device is thin, strong, relatively chemically inert and mechanically stable. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: (1) a method of analyzing a target polymer comprising introducing the target polymer to the device, allowing the target polymer to move with respect to the pore to produce a signal, and monitoring the signal corresponding to the movement of the target polymer with respect to the pore and analyzing the target polymer; and (2) a method of identifying a membrane molecule-interacting compound comprising contacting the membrane molecule of the device with a compound and measuring at least one activity of the membrane molecule in the presence of the compound, where a change in activity in the presence of the compound indicates that the compound interacts with the membrane molecule. DESCRIPTION OF DRAWING(S) - The figure shows schematic diagram of the use of membrane fusion to form a graphene-supported bilayer.