• 专利标题:   Graphene oxide/copper selenide/polyethylene glycol nanocomposite for preparing cancer photo-thermal treatment drug comprises surface-modified graphene oxide copper selenide nanoparticles and polyethylene glycol.
  • 专利号:   CN104027807-A, CN104027807-B
  • 发明人:   YANG S, GUO L, ZENG B, WU H, SHI B
  • 专利权人:   UNIV SHANGHAI NORMAL
  • 国际专利分类:   A61K041/00, A61K047/48, A61P035/00
  • 专利详细信息:   CN104027807-A 10 Sep 2014 A61K-041/00 201480 Pages: 9 Chinese
  • 申请详细信息:   CN104027807-A CN10245566 04 Jun 2014
  • 优先权号:   CN10245566

▎ 摘  要

NOVELTY - A graphene oxide/copper selenide/polyethylene glycol (PEG) nanocomposite comprises surface-modified graphene oxide copper selenide nanoparticles prepared by oxidizing graphene and copper selenide nanoparticles, and PEG which is deposited on the oxidized surface-modified graphene oxide copper selenide nanoparticles through ligand exchange. USE - For preparation of cancer photo-thermal treatment drug (claimed) for photo-thermal therapy. ADVANTAGE - The graphene oxide/copper selenide/polyethylene glycol (PEG) nanocomposite has a high photo-thermal conversion efficiency, and good photothermal. The nanocomposite is prepared by simple operation, using easily obtained raw material and with low cost, and is suitable for industrial production. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for the preparation of the graphene oxide/copper selenide/polyethylene glycol (PEG) nanocomposite involving: adding oxide nano graphene dispersion in a hydrophobic solvent, and dissolving cuprous chloride as copper source and selenium urea as Se source in the solvent at high temperature of 220-240 degrees C for 10-30 minutes, to obtain graphene oxide/copper selenide, and adding PEG to improve solubility in water, to obtain graphene oxide/copper selenide/PEG nanocomposite.