• 专利标题:   Ternary composite antibacterial material for inhibiting Escherichia coli, Staphylococcus aureus and other pathogenic bacteria, comprises reducing graphene oxide as substrate, and silver particle-supported molybdenum disulfide nanosheets.
  • 专利号:   CN110583691-A
  • 发明人:   HUANG H, YU Y, LI J, ZHENG J
  • 专利权人:   UNIV NANJING TECHNOLOGY
  • 国际专利分类:   A01N059/00, A01N059/16, A01P001/00, A61K033/24, A61K033/38, A61K033/44, A61K047/69, A61P031/04
  • 专利详细信息:   CN110583691-A 20 Dec 2019 A01N-059/00 202004 Pages: 11 Chinese
  • 申请详细信息:   CN110583691-A CN10886069 19 Sep 2019
  • 优先权号:   CN10886069

▎ 摘  要

NOVELTY - Ternary composite antibacterial material comprises reducing graphene oxide as used as a substrate, and silver particle-supported molybdenum disulfide nanosheets covering or embedding reducing graphene oxide substrate. USE - Ternary composite antibacterial material for inhibiting Escherichia coli, Staphylococcus aureus and other pathogenic bacteria (claimed). ADVANTAGE - The ternary composite antibacterial material has a typical layered structure of a two-dimensional material, and the silver particles are successfully loaded and distributed uniformly. It has a good inhibitory effect on Escherichia coli, Staphylococcus aureus, and its silver ions release slowly and stably. It has a long-lasting bacteriostatic effect. It has broad application prospects in the fields of biomedicine and food antibacterial packing. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the ternary composite antibacterial material, which involves: (A) dispersing a single layer of graphene oxide powder in ultrapure water, and obtaining a graphene oxide dispersion by ultrasonic and magnetic stirring; (B) adding the reducing agent sodium borohydride into the graphite oxide dispersion on water bath at 60-100 degrees C temperature and maintaining magnetic stirring for 1-2.5 hours, after the reaction completed, cooling to room temperature, centrifuging and washing with water, and drying to finally obtain a reduced graphene oxide material powder; (C) dispersing molybdenum disulfide powder and polyethylene glycol together in ultrapure water, and ultrasonically and magnetically stirring to obtain a molybdenum disulfide dispersion liquid; (D) dispersing the reduced graphene oxide powder in ultrapure water to obtain a reduced graphene oxide dispersion; (E) mixing the reduced graphene oxide dispersion with the molybdenum disulfide dispersion, ultrasonically and magnetically stirring to obtain a first reaction mixture; (F) keeping the first reaction mixture in an oil bath at 110-200 degrees C temperature and magnetically stirring for 10-16 hours, after the reaction completed, cooling to room temperature, centrifuging, washinmg with water, and drying to obtain composite material; (G) reducing the reduced graphene oxide powder, mixing molybdenum disulfide dispersion, and adding silver nitrate and the reducing agent L-ascorbic acid while stirring, and adjusting 4-5 pH with hydrochloric acid to obtain a second reaction mixture; and (H) keeping the second reaction mixture at 120-220 degrees C temperature in an oil bath and magnetically stirring for 10-16 hours, after the reaction completed, cooling the reaction mixture to room temperature, centrifuging, washing with water, and drying to obtain the product.