▎ 摘 要
NOVELTY - A wearable sweat sensor system comprises a wearable sweat sensor patch applied to a human subject's skin, a multi-inlet microfluidic sweat sampling and collection module for collecting an induced sweat sample for analysis, a metabolite detection module for identifying concentrations of target metabolites present in the collected sweat sample, and a smart device for analyzing the detected metabolite concentration and displaying information based on the analyzed metabolite concentration. USE - Wearable sweat sensor system for monitoring key metabolites. ADVANTAGE - The wearable sweat sensor system is lightweight, cost-effective, comfortable, non-invasive, and easily worn by a human patient as needed for extended period of time, and measures key biomarkers comparably to blood testing. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: 1. Sweat sensor patch (100), which comprises an iontophoresis module for administering sweat induction agent that stimulates production of sweat, a multi-inlet sweat sampling and collection module for collecting an induced sweat sample, a molecularly imprinted polymer (MIP) organic compound sensor module for analyzing the induced sweat sample, and a metabolite detection module for identifying concentrations of target metabolites present in the collected sweat sample; 2. Wearable biofluid sampling system; 3. A sweat induction and collection method, which involves: (i) applying a stimulating agent to a human sweat gland, where the stimulating agent stimulates production of sweat sample; (ii) collecting the stimulated sweat in a multi-inlet microfluidic module; (iii) emptying the collected sweat sample from the reservoir; (iv) collecting a fresh sweat sample in the multi-inlet microfluidic module; and (v) repeating steps three and four over a period of time to collect refreshed sweat samples; and 4. MIP detection method, which involves: (a) polymerizing functional monomers with template molecules; (b) forming a complex with target molecule using the functional monomer and a crosslinker; (c) embedding a functional group of the functional monomer and crosslinker in a polymeric structure laser engraved graphene (LEG); (d) extracting the target molecule; and (e) revealing binding sites on an LEG-MIP electrode that are complementary in size, shape, and charge to the target molecule. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of wearable sweat sensor. 100Sweat sensor patch 102Backing layer 104Biosensor array 106Electrodes 108Biosensor