• 专利标题:   Nanocomposite, useful for delivering camptothecin to tumor cell of human body, comprises graphene oxide-grafted polymer loaded with medical active ingredient at specified temperature, where ingredient is released at specified rate.
  • 专利号:   KR2014112314-A, KR1462331-B1
  • 发明人:   PARK S Y, THANGAVELU K
  • 专利权人:   UNIV KYUNGPOOK NAT IND ACAD COOP FOUND
  • 国际专利分类:   A61K031/4745, A61K047/30, A61K047/48, A61K009/16
  • 专利详细信息:   KR2014112314-A 23 Sep 2014 A61K-047/48 201468 Pages: 15
  • 申请详细信息:   KR2014112314-A KR026913 13 Mar 2013
  • 优先权号:   KR026913

▎ 摘  要

NOVELTY - Nanocomposite comprises graphene oxide-grafted polymer loaded with a medical active ingredient at 72 degrees C, where the medical active ingredient is released at a rate of more than 50% at low critical solution temperature (LCST) or at released at a rate of less than 25% at less than LCST. USE - The nanocomposite is useful for delivering an anti-cancer drug i.e. camptothecin (all claimed) to tumor cell of a target i.e. human body. ADVANTAGE - The water-soluble nanocomposite efficiently delivers the drug with excellent bio-solubility and stability to the site of the target in a controlled manner with reduced side effects. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for producing nanocomposite, comprising grafting polymer with graphene oxide.