▎ 摘 要
NOVELTY - The synthesizing method of hydrogenated quinidine involves (1) dispersing graphene oxide in deionized water to prepare solution (A), (2) dissolving potassium hydroxide and chloroacetic acid in deionized water to prepare solution, adding to the prepared solution (A), stirring, and filtering after finishing the reaction to obtain carboxylated graphene, (3) dispersing the prepared carboxylated graphene in deionized water to prepare solution (B), (4) dissolving pure platinum powder in hydrochloric acid and sodium chlorate solution, adding sodium succinate, and stirring and mixing with the solution (B), heating, stirring, cooling, and removing the solvent from the reaction liquid to obtain catalyst, and (5) dissolving quinidine in organic solvent, adding catalyst, stirring, adding sodium borohydride solution, reacting, extracting the reaction solution with ethyl acetate, and re-crystallizing. USE - Synthesizing method of hydrogenated quinidine. ADVANTAGE - The method enables synthesis of hydrogenated quinidine with low energy consumption and high yield, by simple operation and short reaction process. DETAILED DESCRIPTION - The synthesizing method of hydrogenated quinidine involves (1) dispersing graphene oxide in deionized water to prepare solution (A), (2) dissolving potassium hydroxide and chloroacetic acid in deionized water to prepare solution, adding to the prepared dispersion (A), stirring at room temperature to react for 1-5 hours, and filtering after finishing the reaction to obtain carboxylated graphene, (3) dispersing the prepared carboxylated graphene in deionized water to prepare solution (B), (4) dissolving pure platinum powder in hydrochloric acid and sodium chlorate solution, adding sodium succinate, and uniformly stirring and mixing with the solution (B), slowly raising the temperature to 40-50 degrees C, stirring and reacting for 20-60 minutes, cooling to room temperature after finishing the reaction, and removing the solvent from the reaction liquid to obtain catalyst, and (5) dissolving quinidine in organic solvent, adding the prepared catalyst, stirring, continuously adding sodium borohydride solution with concentration of 10 %mass, reacting for 10-40 minutes, extracting the reaction solution with ethyl acetate after the reaction is completed, and re-crystallizing.